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It was found out that naltrexone and bupropion combined, which can be marketed in the future as Contrave, have better weight loss results than diet and exercise alone.
Using two separate drugs to lose weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the those who go through it you need to err along the side of caution and let the FDA do its job and demand some research be done so that the public understands the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to earn money and that they would say almost anything to keep people on the medications.
Researchers found out that participants taking this drug for a year, lost excess weight within one month and have kept the weight off through the 56 weeks from the study. Contrave is a combination with the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs that are made up of more than one active ingredient, which can make them more effective and safer.
Combo-pilling will be the newest fad or in addition to this the newest ahead under scrutiny and therefore it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is becoming popular is the fact that by right now there aren't long term prescription weight loss supplements that have been authorized by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be approved by the FDA.
Seizures really are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug may also raise blood pressure levels and heartrate, and mustn't be used in individuals with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.
The FDA also warned that Contrave can raise hypertension and pulse rate and must not used in patients with uncontrolled high blood pressure level, as well as by anyone with heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients having a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients to the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.
"This is the first drug I'm alert to that targets the appetite and reward centres inside brain," he said.