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understanding problem gamblers a practitioners guide to effective intervention

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understanding problem gamblers a practitioners guide to effective interventionFor most people it is an enjoyable, exciting entertainment, but for a minority it becomes a destructive dependency. This practical book is designed for those involved with a problem gambler, such as clients, partners or family members. Copyright Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: This article has been cited by other articles in PMC. Abstract Introduction International prevalence rates for problem gambling are estimated at 2.3. Problem gambling is a serious global public health concern due to adverse personal and social consequences. Previous research evaluating the effectiveness of psychological interventions for the treatment of problem gambling has been compromised by methodological limitations, including small sample sizes and the use of waitlist control groups. This article describes the study protocol for a pragmatic randomised controlled trial (RCT) evaluating the effectiveness of cognitive-behavioural therapy (CBT), behaviour therapy (BT), motivational interviewing (MI) against a non-directive supportive therapy (NDST) control, in treating problem gambling. Methods and analysis This study was a mixed-methods design, with a parallel group, pragmatic RCT as the primary component, and embedded qualitative studies conducted alongside. A total of 297 participants were recruited from the community in Victoria, Australia. Individuals aged 18 years and over, could communicate in English and wished to receive treatment for a gambling problem were eligible.http://www.siapsrl.com.ar/resources/original/diehard-portable-power-950a-manual.xml

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Participants were randomly allocated in to 1 of the 4 psychological interventions: CBT, BT, MI and NDST. Repeated measures were conducted at pretreatment and post-treatment, and 6 and 12 months post-treatment. The statistical analysis will use an intention-to-treat approach. Multilevel mixed modelling will be used to examine changes in the primary outcome measures: gambling symptom severity, using the Gambling Symptom Assessment Scale, and gambling behaviours (frequency, time and expenditure). Secondary outcomes are depression, anxiety, stress and alcohol use. Ethics and dissemination This study was approved by the Victorian Department of Justice, Monash University and the University of Melbourne Human Research Ethics Committees. Findings will be reported in a government report, peer-reviewed publications and conference presentations. Trial registration number Current Controlled Trials ISRCTN01629698. Keywords: PUBLIC HEALTH, PRIMARY CARE, MENTAL HEALTH Strengths and limitations of this study The main strength of this trial is the use of a non-directive supportive therapy as a control group, enabling the examination of the durability of therapeutic effects. This study will also significantly contribute to the field through the use of qualitative methods to gain a better understanding of the treatment process that were perceived to be effective from the participants viewpoint. As a pragmatic randomised controlled trial, this study is able to provide evidence on the effectiveness of these interventions in real-life settings. The use of less restrictive eligibility criteria will also improve the validity of the findings, as this sample will be representative of the problem gambling population. The use of several psychologists may be a limiting factor in this study design; however, therapist effects will be controlled for in the analysis.http://doggystylzgrooming.com/admin/photos/diehard-power-inverter-400-manual.xml Introduction Various terms have been used to describe problematic levels of gambling, including disordered gambling, pathological gambling and problem gambling. According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V), a gambling disorder is characterised by “persistent and recurrent problematic gambling behaviour leading to clinically significant impairment or distress.” 1 In the context of this study, the term problem gambling is used to describe a severe level of gambling, based on a continuum of gambling-related harm. 2 This continuum ranges from non-problem gambling, to problem gambling, where problem gambling is characterised by difficulties in limiting money and time spent on gambling and leads to adverse consequences for the gambler, others or the community. 2 Psychological interventions have been the most examined, to date. One of the most common psychological treatments is cognitive-behavioural therapy (CBT), combining the cognitive and behavioural models for problem gambling. The cognitive model of problem gambling purports that gamblers have certain erroneous beliefs about gambling, which are based on false assumptions and biased information processing. 12 Cognitive interventions aim to correct erroneous beliefs (eg, belief that they have control over luck), by using techniques such as cognitive restructuring to correct any cognitive distortions and biases. Generally, the behavioural model of problem gambling claims that gambling is a learned maladaptive behaviour. Behavioural interventions use classical and operational conditioning techniques to reduce the excitement and arousal linked with gambling. 13 These techniques include exposure, desensitisation and aversive techniques, problem solving training and relapse prevention.Previous RCTs in problem gambling have been limited by small sample sizes. A recent review of RCTs of psychological interventions for problem gambling found that the average sample in these studies was 89 participants, ranging from 13 to 231, 20 with many studies lacking the statistical power required to detect change. Further complicating this issue are the high attrition rates in this field.A review by Lewin et al 29 emphasised the importance and contribution qualitative studies can make to RCTs, especially where the interventions evaluated are complicated. Qualitative studies can assist in understanding the effects of these interventions as well as the mechanisms through which change occurs. This is particularly relevant in the problem gambling field, as research has indicated how diverse and heterogeneous this population is. 30 Overall, further research is required to demonstrate the relative effectiveness of different psychological interventions, as this has not yet been well examined. Furthermore, RCTs of problem gambling interventions have had various methodological limitations, which need to be addressed in future research. As such, a pragmatic RCT was designed to address these methodological limitations. This article describes the study protocol of this pragmatic RCT, entitled the PROblem Gambling RESearch Study (PROGRESS). This article includes a description of the methods of the RCT and embedded qualitative studies and the baseline characteristics of the RCT sample. Trial objectives The primary aim of this study was to determine the effectiveness of CBT, behaviour therapy (BT) and MI in reducing gambling behaviours and gambling symptom severity, at post-treatment, 6 and 12 months follow-up, when compared with an active control condition, non-directive supportive therapy (NDST). A secondary aim is to explore participants’ experiences of treatment. Methods Study design This study was a mixed-methods design, with a parallel group, pragmatic RCT as the primary component, and embedded qualitative studies conducted alongside.https://mugtama.com/images/colt-defender-bb-gun-manual.pdf Figure 1 details the flow of participants through the study, according to Consolidated Standards of Reporting Trials (CONSORT). Details relating to the RCT will be described first, followed by a separate description of the embedded qualitative studies. Ethics approval for this study was obtained from the Department of Justice Human Research Ethics Committee, Monash University Human Research Ethics Committee and the University of Melbourne Human Research Ethics Committee. Open in a separate window Figure 1 CONSORT diagram. Recruitment and participants Participants were recruited from the community in Victoria, Australia, using public advertisements in major newspapers, gambling venues and online (eg, Google advertisements and Facebook and university websites). Attempts were also made to recruit participants through Gamblers Help services. Participant recruitment occurred between January 2013 and February 2014. Individuals were eligible to participate if they were aged 18 years and over, could communicate in the English language, lived in Victoria and wished to receive treatment for a self-identified gambling problem. Individuals were excluded if they were unable to understand and provide informed consent, were at risk of self-harm or had received treatments for their gambling problems in the past 12 months from a counsellor or therapist. People with comorbid mental health disorders were not excluded from the trial. Excluding participants based on this would have led to a sample that is unrepresentative of most treatment populations due to the high rates of comorbid mental health disorders in this population. Individuals that were interested in participating contacted the research team via a free of charge 1800 telephone number or via a designated study email. Trained research assistants were responsible for responding to any queries via telephone or email. These research assistants were also responsible for screening potential participants for eligibility. The screening process was only conducted over the telephone. Randomisation To ensure equal numbers across the four interventions, participants were randomised using a permuted block design. The block sizes were randomly varied to reduce the chance of the research team recognising the assignment schedule. 31 The National Health and Medical Research Council (NHMRC) Clinical Trials Unit, an external and independent unit, was responsible for generating the randomisation schedule used in this study. Randomisation occurred after the pretreatment assessment interview. A research assistant was responsible for contacting the NHMRC clinical trials unit, via telephone, to ascertain the allocated intervention and was then responsible for allocating a psychologist to each participant. This research assistant was not involved in any of the post-treatment and follow-up data collection. Interventions Participants in each intervention received up to six individual, face-to-face sessions with a registered psychologist. The interventions in this RCT were each guided by a manual. All of the treatment sessions were audio-recorded for treatment fidelity purposes. A randomly selected subset of the treatment sessions were rated by two people, independent of the research team. A treatment fidelity checklist was developed for this purpose, with the same checklist used for all sessions. A detailed description of the interventions is provided below. To clearly outline the differences between the interventions, see table 1 for an outline of the session structure per intervention. Table 1 Session structure of interventions Intervention Session 1 Session 2 Session 3 Session 4 Session 5 Session 6 CBT History taking, assessment and goal formation Gambling education and self-management techniques Identifying and challenging gambling-specific erroneous cognitions Relapse prevention BT History taking, assessment and goal formation Gambling education and self-management techniques Imaginal exposure and reducing urges to gamble Relapse prevention MI Engaging with the participant, explaining the treatment, providing assessment feedback and history taking Check in with the participant and determine their goal for the session. The exact content of each session will differ depending on the participant's readiness to change and their ambivalence and resistance towards change. Underpinning each session will be the principles of MI, including expressing empathy, rolling with resistance, supporting self-efficacy and developing discrepancy NDST Engaging and checking in with the participant to determine what they hope to focus on in the session. Each session will be underpinned by the principles of unconditional positive regard, genuineness, empathic understanding, reflective listening, staying entirely within the participant's frame of reference and avoidance of volunteering leading questions, interpretations, suggestions or guidance Open in a separate window BT, behaviour therapy; CBT, cognitive-behavioural therapy; MI, motivational interviewing; NDST, non-directive supportive therapy. Cognitive-behavioural therapy Session 1: History taking, assessment and goal formation The initial session involved general history taking and assessment. A treatment plan was developed based on the participant's goals for treatment and the information gathered during the initial assessment. Self-management techniques and strategies to deal with these triggers and urges to gamble were also addressed. These include strategies like avoiding triggers, controlling cash and thinking of alternate activities that they can do instead of gambling. Once identified, the aim was to challenge these gambling-specific erroneous cognitions. This session also involved problem solving skills training. Session 6: Relapse prevention The main aim of this session was to assist the client in understanding and preventing future relapses. This session focused on alternate activities an individual could engage in to divert their attention away from gambling and help achieve a balanced lifestyle that can minimise the chances of relapsing in the future. Behavioural therapy Session 1: History taking, assessment and goal formation The initial session involved general history taking and assessment. This technique requires the participants to visualise real-life scenarios where they are tempted to gamble. By using relaxation techniques and discussing various alternative activities to gambling (eg, making plans with family to watch a movie), imaginal exposure aims to help the participants deal with their gambling triggers in real life. However, underpinning each session were the basic principles of MI, including expressing empathy, rolling with resistance, supporting self-efficacy and developing discrepancy. 19 The main priority for the first session was to engage with the participant and to develop a safe and positive environment. During this session, participants were offered feedback on their initial baseline assessment as a way of generating discussion. Each subsequent session began by checking in with the client and determining what they hoped to focus on in each session. Broadly, the focus of these sessions were on the participant's gambling behaviour, but this could have been narrowed down depending on the participant's main concerns and treatment goals. By the end of the six sessions, participants were assisted by their psychologist to navigate through the change process and to develop a realistic and achievable plan to help change their problematic gambling behaviour. As such, it was decided that current practising psychologists would be utilised for the delivery of treatment in this RCT. The psychologists were required to have current registration with the Australian Health Practitioner Regulation Agency (AHPRA), have experience in delivering one of the four types of psychological interventions and experience in treating individuals with gambling problems or addictive disorders. Prior to starting work on this trial, the psychologists were required to attend a training session, where they were briefed on the study processes and how to deliver interventions for a research study. Each psychologist only delivered one type of treatment for this trial as this would assist with treatment adherence. Treatment setting and referrals The treatment sessions were delivered from the psychologists’ current practice. While not an exclusion criterion, participants were informed that as part of this study they would need to be able to travel to see their allocated psychologist. The trained research assistant who was responsible for the randomisation process was also responsible for allocating a psychologist to each participant and sending referral documents to the participants and psychologists. A psychologist was allocated to a participant based principally on geographical proximity. Outcome measures Primary outcomes for this study were changes in gambling symptom severity and gambling behaviours (frequency, time and expenditure). Secondary outcomes were changes in depression, anxiety, stress and alcohol use. See table 2 for a description of all measures, including the primary and secondary outcomes, predictor variables and general descriptive information (eg, sociodemographic and clinical history characteristics), and the time points at which they were assessed. Urge subscale scores range from 0 to 16. A score of 8 or more indicates a strong likelihood of hazardous or harmful alcohol consumption. Each subscale score ranges from 5 to 20. Subscale scores are transformed to range from 0 to 100. Response options include five statements reflecting the stages of change: precontemplation, contemplation, preparation, action and maintenance X X X X Substance use 43 Participants’ substance use will be assessed using nine items relating to various substances, including tobacco, cannabis, cocaine, amphetamines, inhalants, opioids, hallucinogens, sedatives or sleeping pills and any other illicit substances. The cognitive-experimental processes include consciousness raising, self-re-evaluation, social liberalisation and environmental re-evaluation. Sociodemographic characteristics, needed to confirm eligibility, were collected during the screening process (date of birth, gender, country of birth, language spoken at home and postcode of current residence). All other measures were collected at pretreatment, post-treatment and at 6 and 12 months post-treatment. This included various sociodemographic characteristics (marital status, employment status, household composition, number of children, employment status, current occupation, education level, personal income and management of income) and clinical history variables (current medication and previous or current treatment for gambling, other addictions and mental health disorders). Trained research assistants, who were blinded to the treatment allocation of participants, conducted all of the data collection interviews over the telephone. Data management All data and participant information are stored in password protected files, with only the research team given access. Microsoft Access was used to record any personal information required to contact participants for follow-up data collection. The outcome-related data were entered in to the Statistical Package for the Social Sciences (SPSS) V.21, 47 with no identifiable information. After entry, a random subsample of data collection interviews at each time point was checked to ensure the accuracy of the data entry. Furthermore, statistical checks were conducted during the data cleaning process. The hard copies of the data collection interviews are stored in locked filing cabinets, with only members of the research team given access. Statistical analysis In this pragmatic RCT, our primary analysis will be conducted using an intent-to-treat approach, and therefore include all randomised participants. Baseline characteristics of participants in the four treatment groups will be reported using frequency distributions and descriptive statistics including measures of central tendency and dispersion. A sample of repeated measurements on the same group of participants was collected (baseline, immediately post-treatment, 6 and 12 months post-treatment), so the main analysis will be multilevel mixed modelling to examine the primary and secondary outcome measures. Random effects will account for within-participant correlation; fixed effects will be time and intervention group and the interaction of intervention and time. This is anticipated based on typical samples using these measures. To improve normality of the distribution, these data will be transformed using a log (base 10) function and the transformed data used in the main analyses. Qualitative studies Two qualitative studies were conducted alongside the main RCT. Experiences of treatment study In order to obtain more detailed insight into the experiences of the participants, qualitative data were collected with a subsample of the participants who enrolled in the RCT. The aim of this qualitative study was to examine the perceptions and experiences of treatment of the participants in each of the four arms of the RCT. In particular, the barriers and enablers of change over time will be explored to further clarify why there may be heterogeneity in treatment outcomes. During the screening process, all individuals were informed that additional, in-depth interviews with a subgroup of participants would be conducted. From those that indicated interest in participating in the additional qualitative interviews, a sampling matrix was constructed to recruit a representative sample of the larger RCT according to treatment arm, age, sex and problem gambling severity (using the Problem Gambling Severity Index (PGSI)). All participants signed a separate consent form for these qualitative interviews. See figure 2 for the sampling matrix. Open in a separate window Figure 2 Sampling matrix (PGSI, Problem Gambling Severity Index). A total of 66 participants took part in the pretreatment qualitative interviews. An attempt was made to conduct post-treatment and 12-month follow-up qualitative interviews with all 66 participants. The interviews were conducted face-to-face, and took up to 60 min. Dropout study In many RCTs, there is often a large attrition rate. While the attrition rate is routinely reported in such studies, it is often left unexplained. Reasons for dropping out of a study can be very diverse and can provide important information to complement and explicate the findings. As such, we aimed to identify, where possible, the reasons why participants dropout from a treatment study before it is completed. Participants who dropped out of the study were contacted as a courtesy to thank them for their participation and to investigate their reasons for dropping out. All participants who dropped out before or during the treatment period, or during the 12-month follow-up period were contacted. With participants’ consent, qualitative data were collected via telephone conversations with a trained research assistant, taking approximately 5 min to complete. Descriptive characteristics of the sample from the first qualitative study will be compared with that of the larger RCT sample. All data from both qualitative studies were audio-recorded and transcribed verbatim for entry into NVivo V.9 data management software. 48 Individual transcripts will be independently read and coded by two researchers to enhance rigour. 49 Systematic analysis of the qualitative data will generate a range of broad and more specific key themes related to the central aims of the study. 50 Interview data will also provide in-depth case studies to examine and illustrate individual trajectories through participant's experiences of treatment and post-treatment outcomes over 1 year. 51 The qualitative data will also be analysed in conjunction with the quantitative data as appropriate, with the qualitative data informing the quantitative findings and vice versa. Baseline characteristics of the participant sample A total of 395 individuals expressed an interest in participating in the RCT. Of these, 297 participants were randomised in to the four interventions. See figure 1 for the CONSORT diagram. Baseline characteristics on key variables are presented in table 3. There were no significant differences between the four interventions on any of the key sociodemographic, gambling-related or psychological variables. AUDIT, Alcohol Use Disorders Identification Test; BT, behaviour therapy; CBT, cognitive-behavioural therapy; DASS-21, Depression Anxiety Stress Scale-21; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; G-SAS, Gambling Symptom Assessment Scale; MI, motivational interviewing; NDST, non-directive supportive therapy; PGSI, Problem Gambling Severity Index. Discussion As one of the largest RCTs conducted in the field of problem gambling, this RCT will contribute to the problem gambling treatment evidence base in several ways. This RCT will build on the existing evidence base, by addressing some of the methodological limitations identified in previous RCTs. This trial is one of the first to use a non-specific treatment component control group (ie, NDST). This will enable the examination of the long-term effects of these psychological treatments. Therefore, this RCT will be able to provide much needed evidence in to the durability of any therapeutic effects identified, as well as the patterns of change over time at a group and individual level. One of the major challenges for this study was the potential for high dropout rates that are commonly associated with longitudinal studies, and the problem gambling population, in particular. When calculating an appropriate sample size, the commonly high attrition rates were taken in to account. Based on Melville et al 's 24 review of dropout in psychological treatment for problem gambling, the proposed sample size allowed for the maximum 50 dropout rate, and an intention-to-treat analysis will be conducted. In addition, a parallel qualitative study will identify reasons for dropping out, further contributing important knowledge about treatment attrition. A limitation of the current study may be that all outcome assessments were conducted over the telephone. This trial has the potential to make a significant contribution to the problem gambling treatment field. Through the use of quantitative and qualitative methods, we aim to gain a better understanding, not only of the empirical effectiveness of the treatments, but also the components of the treatment process that participants perceive to be effective. The findings of this trial may have implications for the way current problem gambling treatment services are provided. Acknowledgments The authors would like to acknowledge the work of all the research assistants who assisted throughout this trial. Footnotes Contributors: SAT led the conception and design of the study with contributions from ACJ, CJB, SSM, HR, SF and JE. SSM coordinated the daily running of the project. HR and SF led the qualitative data collection. JE and SSM led the statistical analysis of the baseline data. All authors will participate in the analysis and interpretation of the trial data. SSM led the drafting of the manuscript. All authors reviewed and approved the final manuscript. Funding: This study was originally funded by the Department of Justice. Management of this study was transferred on 1 July 2012 to the Victorian Responsible Gambling Foundation. No warranty is given as to the accuracy of the information. The Victorian Responsible Gambling Foundation specifically excludes any liability for any error or inaccuracy in, or omissions from, this document and any loss or damage that you or any other person may suffer. Competing interests: None declared. Ethics approval: Victorian Department of Justice Human Research Ethics Committee, Monash University Human Research Ethics Committee and the University of Melbourne Human Research Ethics Committee. Provenance and peer review: Not commissioned; externally peer reviewed. References 1. American Psychiatric Association (APA). Diagnostic and Statistical Manual of Mental Disorders. 5th ednAustralia's gambling industries. Report No. 10Annu Rev Public Health Aust N Z J Psychiatry. Dowling NA, Cowlishaw S, Jackson AC et al.. J Pers Disord.