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Mechanisms of gas transport during ventilation by high-frequency oscillation. High frequency oscillatory ventilation vs conventional mechanical ventilation for very-low-birth-weight infants. PubMed CrossRef Google Scholar Kacmarek RM, Malhotra A. High-frequency oscillatory ventilation: what large-animal studies have taught us. PubMed CrossRef Google Scholar Keszler M, Durand DJ. Neonatal high-frequency ventilation: past, present, and future. High-frequency oscillatory ventilation: mechanisms of gas exchange and lung mechanics. PubMed CrossRef Google Scholar Vitali SH, Arnold JH.Springer, Boston, MA. Contact Us to Register Your Interest Already a member. This document may not be copied, reproduced, translated, stored in a retrieval system, transmitted in any form, or reduced to any electronic medium or machine-readable form, in whole or in part, without the written permission of CareFusion. Information in this document is subject to change without notice. All rights reserved. 3100A is a registered trademark of CareFusion Corporation or one of its subsidiaries. All other trademarks are property of their respective owners. To truly understand the operation of this ventilator you must also become familiar with the Operator’s Manual (PART NUMBER 767124). Warnings and Cautions This manual contains important information concerning the prevention of bodily injury and the protection of the equipment. This information may be designated by either Warning or Caution whereby: Warning. A Warning designates information concerning the possibility of bodily injury to the patient, operator or others. Caution! A Caution designates information concerning the possibility of damage to the instrument or to other property. System Description The 3100A HFOV uses a linear motor to oscillate a column of bias flow gas which flows in front of the motor. The column of air creates a pressure within the patient circuit by a variable reduction of the egress of a variable bias flow gas. The gas flow is restricted by the inflation of three mushroom valves mounted on the circuit. Two of the three inflation pressures can be varied to adjust the pressure. The third is a safety valve inflated via a solenoid valve which is de-activated whenever the Mean Airway Pressure is greater than 50 cmH2O or less than 20 of a variable maximum Mean Airway Pressure Alarm. The screws toward the center of the plate attach the plate to a coil of wire which is suspended within a permanent magnet. The coil is then excited with a square wave of adjustable amplitude, frequency and duty cycle. This serves to move the plate via the electromagnetic effects on the coil, causing an oscillating pressure wave dependent on the driving current through the coil and the collapsing or expanding magnetic field. The driving signal is generated by the Driver Controller Module which is located in the lower support column of the device just beneath the Driver Assembly. This module produces a square wave of adjustable frequency, amplitude, offset potential and duty cycle dependent on four user set potentiometers. This line incorporates a positive flow to clear it of any condensation from the humidified Bias Gas. A length of coiled tubing prior to the transducer connection serves to filter out any components of the pressure wave which do not contribute to ventilation. The signal generated by the transducer is detected and conditioned on the Alarm Board which is located at the base of the Electronics Enclosure. If any alarm condition is occurring, the appropriate LED will be lit and the appropriate safety circuit activated. The position of the oscillating Driver is measured by a photo sensor at the rear of the Driver and displayed on the front of the instrument by the Driver Displacement Indicator Board. An elapsed time meter records the time during which the instrument has been turned on regardless of whether or not the driver is activated. Refer to the Theory of Operation Section in the Operator’s Manual for more detailed descriptions. The only ties between electricity and the pressures generated by the 3100A are the solenoid valve and the movement of the oscillating piston. This is very important in the troubleshooting of the system. Component Description Lower Power Supply There are four separate power supplies generated in the Lower Power Supply Assembly. Both of the AC input lines are fused at 500mA. The fuses are used to drive all TTL logic IC’s and all bipolar operational amplifiers. All three are adjustable and the corresponding potentiometers are labeled on the circuit board.Refer to the Interconnect Wiring Diagram for the schematic of this supply. This pressure will open a normally closed pressure switch which is set to open at 30psi. The switch is factory adjusted. In parallel with the switch is a 75 psi pop-off valve which is self resetting. This input gas then goes to PR4 (Pressure Regulator) where the input pressure is then fed to PR1, PR2, PR3, PR6, and PR7 for other functions. This bias flow leaves the electronics enclosure after passing a factory adjusted 5 psi pop-off valve. The air would then be heated and humidified and finally be connected to the underside of the patient circuit assembly. This flow then creates a positive pressure inside the patient circuit. Limit PR2 reduces the pressure from PR4 to approximately.65 psi. There are three paths for air flow. First, there is a fixed orifice to atmosphere. Second, there is a variable orifice to atmosphere. The pressure will be greatest when the variable orifice is fully closed. This is passed to a tee fitting which leads to the pressure sense line and the pressure transducer. This pressure of 135 cmH2O is used to create a flow of air away from the pressure transducer and towards the measuring point on the patient circuit, removing any condensation in the humidified bias flow gas from the humidifier. Dump and Control PR3 reduces the pressure from PR4 approximately 3 - 7 psi under normal operating conditions. This is a user adjustment, located on the right side of the top cover, and should never exceed 7 psi when properly adjusted. This pressure is fed to the normally closed port of solenoid valve one. FV1 at the bottom of the pneumatics enclosure is an adjustable flow restrictor and should be adjusted during the pneumatics alignment procedure in the adjustments section. The other variable orifice is the front panel Paw adjust valve. Closing this restrictor with a clockwise turn will cause greater occlusion of the opening in the patient circuit body at the CONTROL valve. This is the last exit for the bias flow and restricting this outlet will cause a higher pressure in the patient circuit. Driver Cooling The requirements of the compressor air source used to cool the driver are pressure of 40 - 60 PSIG with capability of flow at 10-15 LPM. This input gas is sensed at a 30 psi, normally closed, pressure switch. The switch will open at a pressure greater than 30 PSIG. This input gas is sensed at a 75 psi pop-off valve which will attempt to release pressures above 75 psi. It is self resetting. PR5 reduces this input pressure to approximately 20 psi and feeds into an air flow amplifier on the underside of the driver assembly. This device entrains room air in with the flow of compressed air to enhance the cooling of the driver. For 1.5 ohm driver assemblies (766860) PR5 is set at approximately 15 LPM. This voltage can be measured at TP5. The output characteristics are well beyond those necessary to accurately measure the 15 Hz waveform. Calibration It is necessary to check the calibration of the Pressure Transducer every 2000 hours of operation. Refer to the Maintenance Section of the manual for instructions on this and other regular maintenance requirements. The signal generated by the pressure transducer comes on to the board at J1 pin 1 and is conditioned by three stages of U2, a quad operational amplifier. U2-A is a current amplifier. U2-C provides high frequency filtering and a voltage gain of three. This stage also incorporates an offset adjustment with potentiometer R6. U2-D provides adjustable gain with feedback potentiometer R2. Both potentiometers can be adjusted through the rear panel. TP1 (Test point one) provides easy measurement of the pressure signal using TP6 as a reference ground test point. See the Maintenance Section of this manual for instructions on performing this calibration. Input capacitors C2 and C3 provide input to quad operational amplifier U1-A allowing only changing pressure signals through. U1-C amplifies the negative portions of the pressure signal and this voltage is stored on capacitor C5 due to it is relatively long discharge time through R10. Similarly C1 stores the positive peaks of the pressure signal. The output of U3-C will be proportional to the difference between positive and negative peaks. If the difference voltage is less than approximately.3V DC (6 cmH2O on the digital panel meter labeled “AMPLITUDE”) then diode CR3 will not conduct. This signal originates on the Driver Displacement Indicator Board. Mean Airway Pressure and Alarms Operational amplifier U11-D provides buffering and low pass filtering of the pressure signal. The average pressure or “MEAN AIRWAY PRESSURE” is sent out J2 pin 5 and 6 by way of voltage divider R47 and R40. The front panel Thumbwheel switches for minimum and maximum pressure alarms are adjustable resistance’s which provide feedback for operational amps U3-B and U3-A. The signal is generated by a 10V reference, Q1. The adjustable resistance of the Thumbwheels add 100.Quad comparator U5 is used to determine if a pressure alarm has occurred. The signal “MEAN HI” is used as a positive input on U5-A and U5-B. The negative input of U5-A is the “Set Min” signal selected by a Thumbwheel. The negative input of U5-B will be 20 of the signal “Set Max” selected by the other Thumbwheel. These comparisons determine if a low pressure alarm is occurring and the output of the comparator will be driven low if an alarm is occurring. Conversely, U5-C has its negative input tied to the signal “MEAN HI” and compares it to the full “Set Max” selected by the Thumbwheel switch. And U5-D has “MEAN HI” on the positive input and a fixed 2.5V on the negative. These comparisons determine if a high pressure alarm is occurring. The output of U5-C will be driven low when an alarm is occurring. The 3100A high pressure alarm is set by U5-D when the “MEAN HI” pressure signal rises above 50 cmH2O or 2.5V. This high level will be sensed at OR gate U10-D forcing its output high. This signal is then inverted by U14-B to turn the LED on the Alarm Display Board on. The output of U5-D is also used to trigger U6-A, a monostable multivibrator. This positive pulse will clock the output of U4-A high. U4-A can be reset by the operator pressing the “RESET” switch which will generate a reset pulse to U4-A via Q2. This should only be done after correcting the cause for the high pressure alarm as the DUMP valve will close again and the driver will begin to oscillate again. Keep in mind that the user adjustment to the LIMIT valve should prevent any pressure this high from ever being developed in the patient circuit. This signal is inverted by U14-A and goes to pin 1 of OR gate U10-A. The output of U10-A is high when either “HI AP LIMIT” or “LO AP LIMIT” is active. The signal is inverted by U14-D and goes off the circuit board to the Driver Displacement Indicator Board where it will be NANDed with two other signals to stop the oscillating piston (See DDI Theory of Operation). This signal is called “AP LIMIT” and will cause the oscillator to stop when it is driven low. The output of U14-D is also sent to OR gate U10-B. An active alarm will cause the output of this OR gate to be driven low and transistor Q5 will be turned off de-energizing the solenoid valve in the pneumatics enclosure. This will cause the pressure within the patient circuit to vent to atmosphere. The LO AP LIMIT alarm needs no reset. Once the fault has been corrected the DUMP valve will close and the oscillator will begin to run. The output of U14-D is also sent to AND gate U7-B where it is ANDed with three other signals “OSC STOPPED”, “MIN MAP” and “MAX MAP” which were discussed earlier. A low signal on any of these inputs will drive the output of U7-B low. Turning Q7 on will sound the audio alarm. AND gate U7 provides the input signal when the alarm should be active. These signals are active low. Timer U13 provides a 45 second silence triggered by a front panel switch at J1 pin 4. Power Failure Alarm When power is removed from the 3100A, relay U8 will return to its off position. Relay U9 however, will be kept in the energized state since the battery voltage on the contacts is fed back to the coil. The de-energized contacts allow the battery voltage to drive the audio alarm and the power failure light. Pressing the reset button allows Q3 to conduct breaking the circuit in the normally open U9. Comparator U12-B will generate a battery low signal when the battery voltage falls below 6.5V. Quad op-amp buffers this reference voltage to supply power to the pressure transducer. Signals are active lows. The triangle wave at pin 3 is used to drive the controller circuitry. The negative voltage at pins 4 and 5 determine the frequency of the waveform, and a 10K.This allows the operator to adjust between 3 and 15 Hz. Fine tuning of this frequency can be made with R18 and R19 as measured at TP8. Operational amplifier U1 supplies a signal to the front panel display meter and can be adjusted with R17. If is not necessary to make any adjustments to the potentiometers on the rear of the meter itself. Operational amplifier U2 provides offset and gain adjustments for the triangle wave with potentiometers R1 (Offset) and R2 (Gain). Test point 2 should approximate a 0 - 10V triangle waveform. This signal goes to comparator U4 (LTI011) on the negative input. The positive input is governed by the output of U2-D and the setting of a 10K.JP2 should be jumped. Do not jumper JP1. Fine tuning of the 30 and 50 Inspiratory Time limits can be made with the offset and gain potentiometers R1 and R2. A meter is connected at J22 and J23 for display. R16 adjusts the reading on the meter. The output of comparator U4 is a square wave with the selected frequency and duty cycle ( Inspiratory Time) inspirations during the high portion of the wave at TP7. Each voltage goes to a separate gate on U5. The gates are enabled with a low signal. NAND gate U6-C inverts the square wave so that each gate is enabled alternately. The output of the two gates is tied together and the resultant signal is sent to the inverting input of U2-B. The signal at TP6 should be 10V P-P and centered at 0V. R4 is used as an offset adjustment and R3 is for gain. However, these adjustments are very interactive and repetitive adjustment may be necessary. The signal at TP6 should be present whenever the instrument has power applied. The signal at TP6 is then sent to a 10K.When the start light is lit, the “DISABLE OSC” signal at J1 pin 6 will be at a positive voltage. This is when the oscillator is off. The output of U2-C is the drive signal for the PWM Servo Amplifier discussed later; positive portions of the waveform move the piston forward during inspiration and negative portions of the waveform reverse the piston during expiration. U7 is an optical isolator which provides an enable signal to the PWM Servo Amplifier. Q1, CR1, C17, R40 and C18 reduce and regulate the 40V input from the Lower Power Supply Assembly to 24V. This is then sent through F1, a 500mA slow blow fuse, to power the cooling fan, the solenoid valve and the Pressure Transducer. PWM Servo Amplifier This device is used to provide a safe and reliable switching of the current needed to drive the oscillator. It is extremely efficient (97) and is fully protected against over-voltage, overcurrent, over-heating and any shorting across the oscillator’s coil assembly. Loop gain, current limit input gain and offset can be adjusted. It receives its main drive power directly from the 60V DC power supply located in the Lower Power Supply Assembly. It also takes the drive signal and an inhibit signal from the Driver Controller Board. We do not recommend any service to this subassembly beyond adjustment and inspection of connectors. Choke Board The Choke Board is comprised of two coils which act as a high frequency choke to remove any spurious low level noise from the drive signal, which will be generated by the circuits on the PWM Servo Amplifier. Movement of the Oscillator Mounted through the rear of the driver, the DDI probe generates a current proportional to the position of the driver by sensing light from an LED also mounted on the probe. The light is modulated at approximately 8K Hz by U5 and Q3. Power is sent to both the emitter and detector in the probe via J1 pin 6. The modulated light source is reflected by the rear side of the piston inside the Driver Assembly. The reflections are sensed by the detector on the probe and translated into 8K Hz signal varying in amplitude, depending on the distance between the piston plate and the detector. This signal is buffered by U1 and demodulated by the filtering of C2, C5, C6, R13, R14, R15 and U4. Referring to the schematic, this signal splits at TP1. The top circuit is a high pass amplifier allowing only the fast changes in the resultant amplitude to be passed via C10. The bottom is a low pass amplifier using C12 as the storage capacitor. These signals are then summed by the final stage of U4. The final signal, which can be measured at each output line, activates an 767161 Rev. Potentiometer R7 adjusts the offset or Center LED to be lit when the piston is resting in the center. R1 adjusts the gain of the low pass filter and is used to adjust the far right LED when the piston is at maximum expiration. R4 adjusts the high pass gain and determines the width of the LED display when the oscillator is oscillating. See the 4000 hour procedure for instructions when making these adjustments. There is a procedure for this in the Maintenance Section of the Operator’s Manual. A low at U7 pin 1 will disable the oscillator via U8 and also activate the “STOP OSC ALARM DISABLE”. This signal disables the “OSCILLATOR STOPPED” alarm via the Alarm Board and is active high. The output of U8 is the “DISABLE OSC” signal which is sent to the Driver Controller Board to stop the oscillator. This pin is ACTIVE high, meaning the oscillator will be stopped if this line is high. It is composed of a cylindrical permanent magnet and housing elements with a coil of wire suspended within the magnet via what we refer to as spiders. These spiders are similar to a speaker cone with much deeper convolutions to allow for greater travel. At the front of the coil a plate is mounted. The plate is coupled to the front housing by way of a two piece diaphragm. This diaphragm is the circular rubber ring around the piston plate. A circular piece of foam is between the two diaphragms to keep the diaphragm somewhat rigid. The 1.5 ohm driver should be reworked after every 4000 hours of use to replace the spiders and diaphragms, as they suffer fatigue over time and usage. The 3 ohm driver should be similarly reworked after every 6000 hours of use. Cooling Flow The entire cooling flow required by the Driver Assembly is approximately 40 LPM. 10-15 LPM comes directly from the cooling gas regulator PR5. An additional 25 LPM is entrained into the driver from room air through a device on the bottom side of the Driver referred to as an Air Amplifier. As the 10-15 LPM flow moves through the device, it causes a negative pressure on the bottom air port entraining the additional flow. The Driver is driven by a square wave driver referred to as the Driver Controller Module. The circuitry which senses the temperature is located on the Alarm Board. Ventilator Performance Checks 767161 Rev. After every use inspect and clean, if necessary, the air filter at the base of the ventilator. Four small black snaps release the cover of the filter. Every Seven Years, the Driver Power Module should be replaced. This must be performed by a factory-trained technician. Call Technical Support at 1-800-520-4368 to schedule a service call. At every 500 Hour Interval, replace the input gas filters (one for the blended gas input and one for the cooling gas input). There is a package of ten filters sent with each ventilator. Additional filters may be purchased (PART NUMBER-767163). At every 2000 Hour Interval, preventative maintenance is required.